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Endocrine Abstracts

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ea0081p414 | Pituitary and Neuroendocrinology | ECE2022

Predictive factors of somatostatin receptor ligand response in acromegaly – a prospective study

Diana Ilie Mirela , Tabarin Antoine , Vasiljevic Alexandre , Jean-Francois Bonneville , Moreau-Grange Lucile , Schillo Franck , Delemer Brigitte , Barlier Anne , Figarella-Branger Dominique , Bisot-Locard Segolene , Santos Alexandre , Chanson Philippe , Raverot Gerald

Context: Somatostatin receptor ligands (SRLs) are the cornerstone medical treatment of acromegaly, however many patients remain uncontrolled under SRLs. Well-established predictive markers of response are needed.Objective: We aimed to explore the relationship between responsiveness to SRLs, on one hand, and somatostatin (SST)2A and 5 receptor expression, adenoma granulation, and T2-weighted MRI signal intensity (T2WSI), on the other hand.<p class="ab...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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